Prof. Bräuchle's Research Group - Faculty for Chemistry and Pharmacy

Single Virus Tracing

Live cell imaging and single virus tracing: observation of the infection pathway of a single virus into a living cell and production (self-assembly and budding) of viruses in infected cells for HIV and Herpes

 

Baumgärtel V., Ivanchenko S., Dupont A., Sergeev M., Wiseman P.W., Kräusslich H.-G., Bräuchle C., Müller B., Lamb D.C. Live-cell visualization of dynamics of HIV budding site interactions with an ESCRT component Nature Cell Biology, 13 (2011), 469.

Ruthardt N., Lamb D.C., Bräuchle C.
Single-particle Tracking as a Quantitative Microscopy-based Approach to Unravel Cell Entry Mechanisms of Viruses and Pharmaceutical Nanoparticles
Molecular Therapy 19(7) (2011), 1199.

Ruthardt N., Bräuchle C.
Visualizing Uptake and Intracellular Trafficking of Gene Carriers by Single-Particle Tracking
in "Nucleic Acid Transfection"
Topics in Current Chemistry, Vol. 296/2010
Eds: Bielke W., Erbacher C.
Verlag Springer Berlin/Heidelberg (2010), S. 283-304

Ivanchenko S., Godinez W.J., Lampe M., Kräusslich H.-G., Eils R., Rohr K., Bräuchle C., Müller B., Lamb D. C.
Dynamics of HIV-1 Assembly and Release
PLoS Pathogens 5(11) (2009), e1000652.

Endreß T., Lampe M., Briggs,J.A.G., Kräusslich H.-G., Bräuchle C., Müller B., Lamb D. C.
HIV-1-Cellular Interactions Analyzed by Single Virus Tracing
Eur. Biophys. J. 37 (2008), 1291.

Lampe M., Briggs J.A.G., Endreß T., Glass B., Riegelsberger S., Kräusslich H.-G., Lamb D.C., Bräuchle C., Müller B.
Double-labelled HIV-1 particles for study of virus-cell interaction
Virology 360 (2007) 92.

Seisenberger G., Ried M.U., Endreß T., Büning H., Hallek M., Bräuchle C.
Real-Time Single Molecule Imaging of the Infection Pathway of an Adeno-associated Virus
Science, 294 (2001) 1929.
On this publication in “Science” the following essays were published:
Nature Medicine (2002) 23.
Nature Biotechnology 20 (2002) 35.
J. Cell Biol. 155 (2001) 1094.
Mol. Ther. (2002) 215.

 
 

 

ADDRESS

Ludwig-Maximilians-
Universität München
Department Chemie
Physikalische Chemie I
Butenandtstr. 11
Gerhard-Ertl-Gebäude
D-81377 München
 
Phone: +49-89-2180-77547
Mail: Prof. C. Braeuchle
 
more information...

SELECTED PAPERS

v. Schirnding C., Giopanou I., Hermawan A., Wehl L., Ntaliarda G., Illes B., Datz S., Geisslinger F., Bartel K., Sommer A.-K., Lianou M., Weiß V., Feckl J., Vollmar A.M., Bräuchle C., Stathopoulos G.T., Wagner E., Roidl A., Bein T., Engelke H.
Synergistic Combination of Calcium and Citrate in Mesoporous Nanoparticles Targets Pleural Tumors
Chem 7(2)(2021)480-494Link

Möckl L., Lamb D.C., Bräuchle C. 

Super-resolved Fluorescence Microscopy: Nobel Prize in Chemistry 2014 for Eric Betzig, Stefan Hell, and William E. Moerner
Angew. Chem. Int. Ed. 53(51) (2014), 13972.  Link

Jung C., Schwaderer P., Dethlefsen M., Köhn R., Michaelis J., Bräuchle C. 
Visualization of the Self Assembly of Silica Nanochannels reveals growth mechanism 
Nature Nanotechnology, 6 (2011), 87. Link

Seisenberger G., Ried M.U., Endreß T., Büning H., Hallek M., Bräuchle C.
Real-Time Single Molecule Imaging of the Infection Pathway of an Adeno-associated Virus 
Science, 294(2001) 1929. Link