Prof. Bräuchle's Research Group - Faculty for Chemistry and Pharmacy

Single Molecule Dynamics in Nanoporous Systems

Single molecule dynamics in nanoporous systems: single dye molecules act as nanoscopic reporters diffusing through the pores of the mesoporous silica revealing details of the interaction and the structure of these novel materials. Mechanistical studies of translation, rotation, adsorption and spectral diffusion of single molecules in mesoporous silica structures and other nanoporous systems


Mackowiak S., Bräuchle C.  
Study of Single Molecule Dynamics in Mesoporous Systems, Glasses and Living Cells  
in "Nonequilibrium Statistical Physics of Small Systems: Fluctuation relations and beyond"  
Eds.: Klages R., Just W., Jarzynski C.  
Wiley-VCH Weinheim (2013), p. 393.

Rühle B., Davies M., Bein T., Bräuchle C.
Fluorescence Microscopy Studies of Porous Silica Materials
Z. Naturforsch. (68b) (2013), 423.

Feil F., Naumov S., Michaelis J., Valiullin R., Enke D., Kärger J., Bräuchle C. Single-particle and ensemble diffusivities - Test of ergodicity  
Angewandte Chemie  124(5)  (2012), 1178.  
Angewandte Chemie Internat. Edition  51(5)  (2012), 1152.
Cover picture for Angewandte Chemie Internat. Edition (January 2012, 51(5)

Feil F., Cauda V., Bein T.,*, Bräuchle C.*  
Direct Visualization of Dye and Oligonucleotide Diffusion in Silica Filaments with Collinear Mesopores  
Nano Lett.  12(3)  (2012), 1354.

Rühle B., Davies M., Lebold T., Bräuchle C.*, Bein T.*  
Highly Oriented Mesoporous Silica Channels Synthesized in Microgrooves and Visualized with Single Molecule Diffusion  
ACS Nano  6(3)  (2012), 1948.

Lebold T., Michaelis J., Bräuchle C.*
The complexity of mesoporous silica nanomaterials unraveled by single molecule microscopy
Phys. Chem. Chem. Phys. 13 (2011), 5017.

Jung C.,Schwaderer P., Dethlefsen M., Köhn R., Michaelis J., Bräuchle C.
Visualization of the Self Assembly of Silica Nanochannels reveals growth mechanism
Nature Nanotechnology 6, (2011) 87.
Figure from this publication: cover picture for Nature Nanotechnology, Issue 2 (February 2011 Volume 6 No 2)

Michaelis J., Bräuchle C.
Reporters in the Nanoworld – Diffusion of single molecules in mesoporous materials
Chem. Soc. Rev. 39(12), (2010), 4731.

Bräuchle C.
 Exploring Nanostructured Systems with Single Molecule Probes: From Nanoporous Materials to Living Cells
in "Single Molecule Spectroscopy in Chemistry, Physics and Biology" Nobel Symposium
Springer Series in Chemical Physics, Vol. 96, Part 10
Eds: Gräslund A., Rigler R., Widengren J.
Verlag: Springer Berlin Heidelberg (2010), S. 537-551

Jung C., Bräuchle C.
Visualizing Single-Molecule Diffusion in Nanochannel Systems
in "Single Particle Tracking and Single Molecule Energy Transfer"
Eds.: C. Bräuchle, D.C. Lamb, J. Michaelis
Wiley VCH Weinheim (2009), S. 309.

Feil F., Jung C., Kirstein J., Michaelis J., Li C., Nolde F., Müllen K., Bräuchle C.*
Diffusional and orientational dynamics of various single terrylene diimide conjugates in mesoporous materials
Microporous and Mesoporous Materials 125 (2009), 70.

Lebold T., Mühlstein L.A., Blechinger J., Riederer M., Amenitsch H., Köhn R., Peneva K., Müllen K., Michaelis J., Bräuchle C., Bein T.
Tuning Single-Molecule Dynamics in Functionalized Mesoporous Silica
Chem. Eur. J. 15 (2009), 1661.

Jung C., Kirstein J., Platschek B., Bein T., Budde M., Frank I., Müllen K., Michaelis J., Bräuchle C.*
Diffusion of Oriented Single Molecules with Switchable Mobility in Networks of Long Unidimensional Nanochannels
J. Am. Chem. Soc. 130(5), (2008), 1638.

Jung C., Hellriegel C., Platschek B., Wöhrle D., Bein T., Michaelis J., Bräuchle C.*
Simultaneous measurement of orientational and spectral dynamics of single molecules in nanostructured host-guest materials
JACS, 129(17), (2007), 5570.

Jung C., Hellriegel C., Michaelis J., Bräuchle C.*
Single Molecule Traffic in Mesoporous Materials: Translational, Orientational and Spectral Dynamics
Adv. Mater. 19 (2007) 956.

Zürner A., Kirstein J., Döblinger M., Bräuchle C.*, Bein T.*
Visualizing single molecule diffusion in mesoporous materials
Nature, 450, (2007) 705.

Kirstein J., Platschek B., Jung C., Brown R., Bein T., Bräuchle C.*
Exploration of Nanostructured Channel Systems by Single Molecule Probes
Nature Mat. 6, (2007) 303.




Universität München
Department Chemie
Physikalische Chemie I
Butenandtstr. 11
D-81377 München
Phone: +49-89-2180-77547
Mail: Prof. C. Braeuchle
more information...


v. Schirnding C., Giopanou I., Hermawan A., Wehl L., Ntaliarda G., Illes B., Datz S., Geisslinger F., Bartel K., Sommer A.-K., Lianou M., Weiß V., Feckl J., Vollmar A.M., Bräuchle C., Stathopoulos G.T., Wagner E., Roidl A., Bein T., Engelke H.
Synergistic Combination of Calcium and Citrate in Mesoporous Nanoparticles Targets Pleural Tumors
Chem 7(2)(2021)480-494Link

Möckl L., Lamb D.C., Bräuchle C. 

Super-resolved Fluorescence Microscopy: Nobel Prize in Chemistry 2014 for Eric Betzig, Stefan Hell, and William E. Moerner
Angew. Chem. Int. Ed. 53(51) (2014), 13972.  Link

Jung C., Schwaderer P., Dethlefsen M., Köhn R., Michaelis J., Bräuchle C. 
Visualization of the Self Assembly of Silica Nanochannels reveals growth mechanism 
Nature Nanotechnology, 6 (2011), 87. Link

Seisenberger G., Ried M.U., Endreß T., Büning H., Hallek M., Bräuchle C.
Real-Time Single Molecule Imaging of the Infection Pathway of an Adeno-associated Virus 
Science, 294(2001) 1929. Link