LMU Header LMU M;uuml;nchen Fakultät Chemie und Pharmazie
Faculty Home page  |  IT Services / Webmail  |  Intranet

Prof. Bräuchle's Research Group

Welcome to Prof. Bräuchle's Research Group
Department of Chemistry, University of Munich

14.05.2015: Überreichung der Walther-Nernst-Denkmünze durch den Ersten Vorsitzenden der Deutschen Bunsengesellschaft, Prof. J. Sauer, und Laudatio gehalten von Prof. K. Meerholz/Universität Köln

Curriculum Vitae

Address: Department Chemie and Center for NanoScience (CeNS)
Ludwig-Maximilians-Universität München
Butenandtstr. 11, Haus E
D-81377 Munich, Germany
Contact Mail: Christoph.Braeuchle@cup.lmu.de
Phone: +49-89-2180-77549
Fax: +49-89-2180-77550
Web: www.cup.lmu.de/pc/braeuchle


1968 - 1973: Studies of chemistry and physics at TU Berlin and University Tübingen
1978: Ph. D. in physical chemistry, LMU München
1982: Habilitation in physical chemistry at LMU München

Professional Experience

1979-1980: Postdoc Fellowship IBM San José (California) USA
1981-1983: Teaching und Research Assistant LMU München
1984-1986: C2-Assistant Professor LMU München


1986: C4- Professorship (Chair) Physical Chemistry TU Berlin
1988: C4-Professorship (Chair) Physical Chemistry, LMU München
1994: C4-Professorship (Chair) Physical Chemistry, Director NMI/Univ. Tübingen
Since 1988: C4 Professor (Chair) for Physical Chemistry, LMU München
Since 2012: The official C4 Professorship for Physical Chemistry at the LMU has been prolonged until March 2016 so far

Activities in the Scientific Community

1995-1997: Dean of the Faculty of Chemistry and Pharmacy, LMU München
1998-2000: Member of the senate, LMU München
1994-1997: Head of the GDCh-Photochemistry board
1996-2001: Member of the Review Board of the VW-Stiftung (Intra- and Intermolecular Electron Transfer)
1997-2002: Initiation of the funding program of the VW-Stiftung on "Physics,Chemistry and Biology with Single Molecules"
1997-2002: Member of the Minerva German-Israeli Foundation
2000-2008: Member of the Board of the Center for NanoScience (CeNS) at LMU München
2002-2004: Speaker of the Research Project "ForNano"
2004-2005: Chairman of the Department of Chemistry, LMU München
2004-2012: Speaker: International Elite Graduate School "Nano-Bio-Technology"
2008-2012: Member of the DFG Review Board for Science (Physical Chemistry)
2006-2013: Member of the Board of the Excellence Cluster "Nanosystems Initiative Munich" (NIM) at the LMU München
2006-2013: Coordinator of the Research Area A "Protein Biophysics and Imaging" of the Excellence Cluster "Center for Integrated Protein Science" (CIPS) at the LMU München
2000-2014: Member of the Editorial Board of ChemPhysChem
since 2006: Deutsches Museum Munich: Member of the Board of Trustees
------- Member of numerous advisory committees in Germany and foreign scientific institutions

Research Interests

Spectroscopy, Imaging and Manipulation of Single Molecules and Nanoparticles in Bio- and Nano-Sciences:

  1. Dynamics of single molecules in nanoporous systems: mechanistical studies of translation, rotation, adsorption and spectral diffusion of single molecules in mesoporous silica structures and other nanoporous systems
  2. Development of smart drug delivery systems/nanomedicine: drug delivery with mesoporous silica nanoparticles, polyplexes and lipoplexes/targeting, controlled release and depot effect, live cell imaging of uptake and trafficking in living cells
  3. Live cell imaging and single virus tracing: observation of the infection pathway of a single virus into a living cell and production (self-assembly and budding) of viruses in infected cells for HIV and Herpes
  4. Nanoparticles and human health: live cell imaging of uptake and trafficking of nanoparticles (SiO2, TiO2, ZnO, CeO, Pt etc.) in endothelial cells in an artificial blood circulation model and toxicity measurements
  5. Hybrid nanosystems for light collection: combination of light harvesting complexes (photosynthesis) with metal nanoparticles (plasmons) as advanced biomimetic systems for solar energy collection
  6. Force spectroscopy with single polymer chains, especially polysiloxanes


More than 350 peer-reviewed papers published in scientific journals including high-ranking journals like "Nature", "Science", "Nature Materials", "Nature Nanotechnology", "Nature Cell Biology", "Phys. Rev. Lett." etc. For Details see link Publications.


2015: Walther-Nernst-Denkmünze (awarded by the Deutsche Bunsengesellschaft at the Bunsentagung 2015)
2014: Guest professorship at the University of California San Francisco
2012: Guest professorship at the University of California San Diego
2011: Guest professorship at the University of California Santa Barbara
2009: Elected Member of the Academia Europaea since May 2009
2008: Participant and invited presentation at the Nobel Symposium II "Single Molecules in Chemistry, Physics and Biology", Stockholm/Sweden
2002: Karl Heinz Beckurts Preis 2002
2002: Member of the Bavarian Academy of Sciences
2001: Award at the Munich Business Plan Competition for the contribution "Single Virus Tracing"
1998: Participant and invited presentation at the Nobel Symposium "Single Molecules in Chemistry, Physics and Biology", Stockholm/Sweden
1994: Guest professorship at the University Paris
1993: Guest professorship at the University of California, Los Angeles
1993: Philip Morris Research Award "New Ways in Material Science"

Member of special funding programs

DFG SFB 455: "Viral Functions and Immune Modulation" (finished 2004)
DFG SFB 486: "Manipulation of Matter on the Nanometer Scale" (1999-2009)
DFG SFB 533: "Light Induced Dynamics of Biopolymers" (1999-2007)
DFG SFB 646: "Network in Genome Expression and Maintenance" (2005-2007)
DFG SFB 749: "Dynamik und Intermediate molekularer Transformationen" (2007-2011)
DFG SPP 1175: "Application of ultrasensitive fluorescence methods to the envelopment and budding of viruses with a focus on HIV" (2005-2009)
DFG SPP 1313: "Bioactivity and cellular uptake of distinct nanoparticles in human endothelial cells" (2008-2013)
LMU München NIM: Excellence Cluster "Nanosystems Initiative Munich" (2006-2012), (2012-2017)
LMU München CiPSM: Exzellenzcluster "Center for Integrated Protein Science Munich" (2006-2012), (2012-2017)

"ForNano" Bayerische Forschungsstiftung (2002-2004)
DFG – Normalverfahren
Elitenetzwerk Bayern

DFG SFB = DFG Sonderforschungsbereich
DFG SPP = DFG Schwerpunktprogramm

weitere Informationen hier

Basché Bunsenmagazin

ChemPhysChem Board Member Profile

Universität München
Department Chemie
Physikalische Chemie I
Butenandtstr. 11
D-81377 München
Phone: +49-89-2180-77547
Mail: Prof. C. Braeuchle
more information...

December 2015

CeNS Publication Award 2015 (Category: Best interdisciplinary publication) for publication in J Controlled Release 213 (2015), 79 (Broda E., Mickler F., Lächelt U., Morys S., Wagner E., Bräuchle C.)

The Walther-Nernst-Denkmünze (Deutsche Bunsengesellschaft) was awarded to Prof. Bräuchle at the Bunsentagung 2015


New publication: Switching first contact: photocontrol of E. coli adhesion to human cells, Chem. Comm., accepted (2015) more information... 

New publication: Dendronized Mesoporous Silica Nanoparticles Provide an Internal Endosomal Escape Mechanism for Successful Cytosolic Drug Release, arXiv:1510.05930 [physics.bio-ph] (2015) more information... 

New publication: Genetically designed biomolecular capping system for mesoporous silica nanoparticles enables receptor-mediated cell uptake and controlled drug release, arXiv:1510.03649 [physics.bio-ph] (2015) more information... 

New publication: Highly Efficient siRNA Delivery from Core-Shell Mesoporous Silica Nanoparticles with Multifunctional Polymer Caps, arXiv:1509.03107 [q-bio.SC] (2015) more information... 

New publication: Microdomain Formation Controls Spatiotemporal Dynamics of Cell Surface Glycoproteins, ChemBioChem 16(14), 2023. more information... 

New publication: Assessing potential peptide targeting ligands by quantification of cellular adhesion of model nanoparticles under flow conditions, J Controlled Release 213 (2015), 79. more information... 

New publication: Entwicklung von Nanofähren zur gezielten Krebsbekämpfung mit Hilfe superhochauflösender Lichtmikroskopie, GDCh Aktuelle Wochenschau zum "Internationalen Jahr des Lichts", Woche 16, (2015) more information... 

New publication: Multifunctional Polymer-Capped Mesoporous Silica Nanoparticles for pH-Responsive Targeted Drug Delivery, Nanoscale 7 (2015), 7953. more information... 

New publication: Histidine-rich stabilized polyplexes for cMet-directed tumor-targeted gene transfer, Nanoscale 7 (2015), 5350. more information... 

New publication: Super-Resolution Imaging of ESCRT-proteins at HIV-1 Assembly Sites, PLoS Pathogens (2015), DOI:10.1371/journal.ppat.1004677 more information... 

New publication: Bringing One-Dimensional Photonic Crystals to a New Light: An Electrophotonic Platform for Chemical Mass Transport Visualisation and Cell Monitoring, Mater. Horiz.2 (2015), 299. more information... 

New publication: Cell-Penetrating and Neurotargeting Dendritic siRNA Nanostructures, Angew. Chem. Int. Ed. 53(51) (2015), 1946.
Dendritische Nanostrukturen zur rezeptorvermittelten Aufnahme von siRNA in neurale Zellen, Angew. Chem. 126(51) (2015), 1968. more information... 

New publication: A surface acoustic wave-driven micropump for particle uptake investigation under physiological flow conditions in very small volumes, Beilstein Journal of Nanotechnology 6 (2015) 414. more information... 

New publication: Invited Article Super-resolved Fluorescence Microscopy: Nobel Prize in Chemistry 2014 for Eric Betzig, Stefan Hell, and William E. Moerner, Angew. Chem. Int. Ed. 53(51) (2014), 13972.
Superhochauflösende Mikroskopie: Nobelpreis in Chemie 2014 für Eric Betzig, Stefan Hell und William E. Moerner, Angew. Chem. 126(51) (2014), 14192. more information...